Author

Qiu Chen

Harbin Institute of TechnologyORCID 0000-0003-3079-9207Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Approach:statistical model· 1

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Junjie CheniD· 1 shared Li XiaoiD· 1 shared Lijuan WangiD· 1 shared Xianliang LiuiD· 1 shared Yuze Wang· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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1 shared paperBioinformatics

Junjie ChenORCID

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1 paper

Recent·Most cited

BioinformaticsPLoS Computational BiologyPeer-reviewedJun 5, 2026

Heuristic Multi-site Optimization for Protein Sequence Design using Masked Protein Language Models

Lijuan Wang, Yuze Wang, Qiu Chen…·Junjie Chen

This paper introduces ProtHMSO, a heuristic multi-site optimization framework using masked protein language models to design functional protein sequences more efficiently than existing methods.

2 citations

protein sequencedeep learning

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