Author

Mark Z. Kos

The University of Texas Rio Grande ValleyORCID 0000-0003-3129-7057Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Melanie A. CarlessiD· 2 shared Uchit BhaskariD· 2 shared Asiya Prasla· 1 shared August N. BlackburniD· 1 shared Donna M. LehmaniD· 1 shared Emily ShrimptoniD· 1 shared H.H.H. Göring· 1 shared J.M. Peralta· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersGenomics

Melanie A. CarlessORCID

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3 papers

Recent·Most cited

GenomicsAlzheimer s & DementiaPeer-reviewedSep 1, 2026

A Cell-Type-Resolved Meta-Analysis Reveals Glial DNA Methylation Changes Associated with Aging and Alzheimer's Disease

Uchit Bhaskar, Mark Z. Kos, Melanie A. Carless

This study identifies age- and Alzheimer's disease-associated DNA methylation changes in glial cells using meta-analysis of DNA methylation data across multiple cohorts.

1 citation

humanDNA methylation

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NeurosciencebioRxivPreprintSep 2, 2024

An Efficient Direct Conversion Strategy to Generate Functional Astrocytes from Human Adult Fibroblasts

Uchit Bhaskar, Emily Shrimpton, Jason Ayo…·Melanie A. Carless

This study develops a method to efficiently convert adult human fibroblasts into functional astrocytes using small molecules, achieving high conversion efficiency and astrocyte-like characteristics.

1 citation

humanexperimental assay

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GeneticsbioRxivPreprintJun 9, 2017

Accurate Phasing of Pedigree Genotypes Using Whole Genome Sequence Data

August N. Blackburn, Mark Z. Kos, Nicholas B. Blackburn…·H.H.H. Göring

This paper introduces PULSAR, a method for phasing genotypes in pedigrees using whole genome sequencing data, showing high accuracy and performance in simulations.

DOI 10.1101/148510

whole-genome sequencingstatistical model

𝕏 PostBluesky