Author

Won Seok Chang

University of CincinnatiORCID 0000-0003-3145-4016Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Ara KoiD· 1 shared Dong Seok KimiD· 1 shared Hoon‐Chul KangiD· 1 shared Hyeontae JoiD· 1 shared Hyukpyo HongiD· 1 shared Hyun Yong KohiD· 1 shared Hyung Ju HwangiD· 1 shared Jae Kyoung KimiD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenetics

Ara KoORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintDec 30, 2023

Threshold of somatic mosaicism disrupting the brain function

Jintae Kim, Sang Min Park, Hyun Yong Koh…·Jeong Ho Lee

This study shows that a low number of mTOR mutant neurons can cause seizures in mice, and similar low levels of mosaicism are found in human patients.

1 citation

mousehuman

𝕏 PostBluesky

Systems BiologyPatternsPeer-reviewedDec 26, 2023

Density Physics-Informed Neural Network reveals sources of cell heterogeneity in signal transduction

Hyeontae Jo, Hyukpyo Hong, Hyung Ju Hwang…·Jae Kyoung Kim

The paper develops Density-PINN to infer transduction-time distributions from single-cell gene expression data and finds that heterogeneity in response intensity is reduced when multiple signaling pathways regulate the response.

20 citations

scRNA-seqdeep learning

𝕏 PostBluesky