Sarvesh Nikumbh

COBIND identifies TF co-binding patterns using NMF on TFBS data, revealing both known and novel co-binding configurations across species.

The paper introduces seqArchR, a method using non-negative matrix factorisation to classify promoters by motifs near reference points like TSS, identifying known and novel motifs and their functional roles.

This paper introduces CoMIK, a discriminative method for comparing variable-length genomic sequences, showing improved classification performance and interpretability.