Liquid-Liquid Phase Separation of the m6A RNA ALKBH9B Demethylase: An IDR-dependent Mechanism driving the Alfalfa Mosaic Virus Infection
Victor Gonzalez-Silva, Mikhail Oliveira Leastro, Jose Antonio Navarro, Jesús Á. Sánchez-Navarro, Frederic Aparicio, Vicente Pallás
This study shows that ALKBH9B's liquid-liquid phase separation drives Alfalfa Mosaic Virus infection by forming dynamic condensates that regulate viral RNA binding and accumulation.
bioRxiv · Jul 30, 2026 · PreprintPlant Biology