Daniele Mercatelli

The paper analyzes Monkeypox virus genomes from the 2022 outbreak and compares them to historical and related sequences to determine their origin and genetic characteristics.

The paper identifies key amino acids in SARS-CoV-2 Spike and human ACE2 that affect viral entry and identifies variants in these proteins associated with infection susceptibility.

The paper identifies molecular links between SARS-CoV-2 infection and age-related gene expression changes, highlighting specific genes affected in elderly patients.

The paper introduces a web tool, coronapp, to annotate and monitor SARS-CoV-2 mutations using user-provided genomic sequences and global mutation data.

The paper analyzes the SARS-CoV-2/human interactome to identify key regulatory mechanisms affected by infection, highlighting apoptotic and mitochondrial pathways and ACE2 receptor downregulation.

corto is a lightweight R package for gene network inference and master regulator analysis, benchmarked on human tumor and normal tissue datasets.

This study predicts genomic alterations from gene expression in multiple cancers, showing gene aggregation improves prediction accuracy in noisy single-cell data.