ImmunologyJournal of Clinical InvestigationPeer-reviewed
A20's Linear Ubiquitin Binding Motif Restrains Pathogenic Activation of TH17/22 cells and IL-22 Driven Enteritis
Christopher Bowman, Dorothea Stibor, Xiaofei Sun…·Averil I. Ma
This study shows that A20's M1 ubiquitin binding motif suppresses TH17/22 cell activation and IL-22-driven enteritis by regulating RORγt and epigenetic changes in T cells.
5 citations