Author

Guosheng Yin

University of Hong KongORCID 0000-0003-3276-1392Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Yan ZhangiD· 2 shared Dailin GaniD· 1 shared Peixin TianiD· 1 shared Tsai Hor ChaniD· 1 shared Wanling YangiD· 1 shared Yongfei WangiD· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 11 mutual co-author links

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2 shared papersBioinformatics

Yan ZhangORCID

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2 papers

Recent·Most cited

BioinformaticsBriefings in BioinformaticsPeer-reviewedSep 5, 2022

The GR2D2 Estimator for the Precision Matrices

Dailin Gan, Guosheng Yin, Yan Zhang

The paper introduces the GR2D2 estimator for precision matrices, showing superior performance in high-dimensional sparse settings and identifying cancer pathways in RNA-seq data.

3 citations

bulk RNA-seqstatistical model

𝕏 PostBluesky

GeneticsFrontiers in GeneticsPeer-reviewedAug 19, 2022

Multiethnic Polygenic Risk Prediction in Diverse Populations through Transfer Learning

Peixin Tian, Tsai Hor Chan, Yongfei Wang…·Yan Zhang

This paper introduces TL-Multi, a transfer learning method to improve polygenic risk prediction in non-European populations using European GWAS data, achieving better accuracy than existing methods in SLE and asthma risk prediction.

43 citationstop 2%

humanGWAS summary statistics

𝕏 PostBluesky