Author
University of Notre DameORCID 0000-0003-0535-1259Unclaimed ORCID profile · follow to get notified of new preprints
8 papers
Recent·Most cited
Camden A. Hoover, John Dennen, Dailin Gan…·Cody J. Smith
The paper identifies a genetic maternal effect on microglia development through sox17 mutation in zebrafish, showing that maternal genotype impacts microglia and yolk sac precursor cells.
Xiyu Liu, Le He, Min Zhao…·Siyuan Zhang
The paper maps gene-by-gene-by-environment epistasis in cancer metastasis using CRISPR perturbations in mice, showing niche-dependent fitness and transcriptome convergence.
Chen Chang, Dailin Gan, Lu Diao…·Siyuan Zhang
PAIR combines CRISPR activation and RNA knockdown to study bidirectional gene interactions in DNA repair, revealing strategies to enhance CRISPR-based gene editing precision.
Yufei Cai, Dailin Gan, Hui Zhang, Jun Li
This study evaluates LLM-derived gene embeddings for pathway information recovery using GSEA, showing they encode substantial biological knowledge.
Hannah Gordon, Dailin Gan, Antonio Dolojan…·Cody J. Smith
The paper identifies an IL10 signaling axis that controls microglia lifespan through lysosomal dynamics in zebrafish and mouse models.
Yuting Zhang, Yaoyin Li, Dailin Gan…·Xin Lü
The paper identifies a Smad4-loss-driven neutrophil-enriched subtype in prostate cancer models and shows that targeting epigenetic enzymes can suppress tumor growth.
The paper evaluates open-source text-embedding models as alternatives to OpenAI's for gene analysis, finding some perform as well or better than OpenAI's models.
Dailin Gan, Guosheng Yin, Yan Zhang
The paper introduces the GR2D2 estimator for precision matrices, showing superior performance in high-dimensional sparse settings and identifying cancer pathways in RNA-seq data.