Paul Yousefi

The paper conducts a Bayesian EWAS and GWAS of smoking using DNA methylation data from blood and brain tissues, identifying smoking-related loci and developing an epigenetic biomarker.

This study identifies epigenetic changes and accelerated ageing in multifocal small intestinal neuroendocrine tumours, revealing altered metabolic gene regulation and tumour-specific methylation patterns.

This study uses longitudinal meta-regression to examine how DNA methylation effects on child health outcomes vary by timing, finding larger effects in childhood but noisier associations and time-specific signals.

This paper develops an epigenetic score to objectively measure alcohol consumption using blood-based DNA methylation and validates it across multiple cohorts, finding associations with brain health metrics.

This study conducts a genome-wide association analysis of blood mercury levels in pregnant women and children, identifying suggestive genetic variants but lacking replication across populations.

This paper shows that DNA methylation data can capture ancestry information and introduces a method to infer ancestry from methylation data without genetic data.