Sarah E. Hopkins

This paper develops a novel mouse model of cat allergic rhinitis that recapitulates key clinical features and enables mechanistic and therapeutic studies.

The paper identifies six patients with biallelic IRAK4 variants causing severe neurological autoinflammation without immunodeficiency, expanding the known phenotype of IRAK4-related disease.

This study identifies immune profiles in pediatric cerebrospinal fluid to differentiate pediatric-onset multiple sclerosis from other inflammatory neurological disorders.