Nadezda V. Volkova

The paper develops a tool to assess tumour contamination in normal samples using whole-genome sequencing data, finding contamination in various cancer types and highlighting risks to variant calling.

The paper analyzes mutational spectra in C. elegans DNA repair mutants to identify how different repair pathways affect mutagenesis in germ cells.

This study shows that mutation spectra in C. elegans are shaped by both DNA damage and repair processes, with repair deficiencies altering mutation rates and spectra in many experimental conditions.

The paper identifies mutational signatures linked to DNA mismatch repair deficiency in C. elegans and human cancers, revealing similarities and differences between species.