Molecular BiologybioRxivPreprint
CpG islands act as topological sinks for transcription-induced DNA supercoiling
Catherine Naughton, Andrea Bonato, Michael Chiang…·Nick Gilbert
The paper shows CpG islands act as topological sinks for transcription-induced DNA supercoiling by focusing torsional stress and promoting DNA melting.
DOI 10.64898/2026.08.24.746546