BioinformaticsbioRxivPreprint
Identify compound-protein interaction with knowledge graph embedding of perturbation transcriptomics
Shengkun Ni, Xiangtai Kong, Yingying Zhang…·Mingyue Zheng
PertKGE improves compound-protein interaction prediction using knowledge graph embedding of perturbation transcriptomics, outperforming baselines in cold-start settings and identifying novel therapeutic targets.
DOI 10.1101/2024.04.08.588632