Jiayue-Clara Jiang

This paper benchmarks parameters for TWAS signature-matching to prioritize drug candidates using GWAS data and CMap, showing sensitivity to cell line choice and proposing a best-practice framework.

GWASHub is a cloud-based platform for GWAS meta-analysis that automates data handling, QC, and analysis workflows to improve reproducibility and reduce researcher burden.

This study finds that genetic risk for major depression is associated with higher cardiovascular disease risk in females but not males, even without a depression diagnosis.

This study compares gene expression responses to statins and antidepressants, finding shared immune pathway perturbations and associations with monocyte and platelet metrics.

The paper shows L1PA2 transposons in MCF7 cells provide abundant regulatory sequences, including transcription factor binding sites and transcription start sites, contributing to oncogenic regulation in breast cancer.