Author

Tim C. Roloff

University of ZurichORCID 0000-0003-3435-4723Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:machine learning (classical)· 1 Assay:proteomics· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Adrian EgliiD· 2 shared Helena M. B. Seth-SmithiD· 2 shared Andrea Carolina EntrocassiiD· 1 shared Andreas WendeliD· 1 shared Anette SchreiberiD· 1 shared Axel G. HamprechtiD· 1 shared Dexiong CheniD· 1 shared Deysi López AquinoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMicrobiology

Adrian EgliORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintJul 13, 2026

Machine learning-guided discovery of a conserved plasmid proteomic signature enables MALDI-TOF MS detection of pOXA-48-carrying Enterobacterales

Janko Sattler, Johannes B. Mueller-Reif, Dexiong Chen…·Karsten Michael Borgwardt

The paper develops a machine learning model to detect pOXA-48-carrying Enterobacterales using MALDI-TOF MS spectra, achieving high accuracy across different cohorts.

DOI 10.64898/2026.07.12.738056

humanproteomics

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MicrobiologyMicrobial GenomicsPeer-reviewedFeb 13, 2025

The challenge of sequencing Chlamydia trachomatis and other bacterial STI genomes directly from clinical swabs: the optimum solution

Karina Andrea Büttner, Vera Bregy, Fanny Wegner…·On behalf of the ESCMID Study Group for Mycoplasma and Chlamydia infections (ESGMAC)*

This paper evaluates methods for sequencing bacterial STI genomes from clinical swabs, finding that target enrichment with a pan-genome panel is the most effective approach.

8 citations

humanbulk RNA-seq

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