Helena M. B. Seth-Smith

This study compares resistance development to delafloxacin and ciprofloxacin in Pseudomonas aeruginosa under acidic and neutral pH conditions, finding a higher genetic barrier to resistance for delafloxacin but potential cross-resistance to ciprofloxacin.

The paper develops a machine learning model to detect pOXA-48-carrying Enterobacterales using MALDI-TOF MS spectra, achieving high accuracy across different cohorts.

This study tracks Legionella pneumophila in a building's water system over 25 years, finding all isolates belong to ST45 and show limited genetic diversity despite repeated decontamination efforts.

This paper evaluates methods for sequencing bacterial STI genomes from clinical swabs, finding that target enrichment with a pan-genome panel is the most effective approach.

This paper reports whole genome sequences of Chlamydia trachomatis from Argentina and Finland, identifying a novel ompA-genotype L4 clade and a non-LGV strain associated with anorectal proctitis.

This paper reclassifies SHV β-lactamase alleles in K. pneumoniae genomes based on mutations, improving genotype-phenotype understanding and updating the Kleborate tool.

The paper analyzes Ct genomic diversity and identifies SNPs associated with ocular localization and disease severity in a West African trachoma-endemic population.