Author

Olga S. Sizova

University of TorontoORCID 0000-0003-3441-9064Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:CRISPR screen· 2 Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Research Focus:genome assembly· 1 Approach:statistical model· 1

Frequent Co-Authors

Amy H.Y. TongiD· 3 shared Andrea Habsid· 3 shared Brenda AndrewsiD· 3 shared Chad L. MyersiD· 3 shared Charles M. BooneiD· 3 shared Jason MoffatiD· 3 shared Keith A. LawsoniD· 3 shared Kevin R. BrowniD· 3 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersSystems Biology

Amy H.Y. TongORCID

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3 papers

Recent·Most cited

Systems BiologybioRxivPreprintJun 30, 2025

A global genetic interaction map of a human cell reveals conserved principles of genetic networks

Maximilian Billmann, Michael Costanzo, Xiang Zhang…·Charles M. Boone

The paper constructs a genome-scale genetic interaction network from 4 million double mutants in HAP1 cells, revealing conserved genetic network principles across species and uncovering novel gene functions and cancer dependencies.

5 citations

humanexperimental assay

𝕏 PostBluesky

Systems BiologyNature MetabolismPeer-reviewedJun 1, 2020

Systematic mapping of genetic interactions for de novo fatty acid synthesis

Michael Aregger, Keith A. Lawson, Maximilian Billmann…·Jason Moffat

This study maps genetic interactions in FASN-deficient cells to identify genes involved in lipid uptake and metabolic adaptation.

113 citationstop 2%

humanCRISPR screen

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Systems BiologybioRxivPreprintMar 16, 2017

Evaluation and Design of Genome-wide CRISPR/Cas9 Knockout Screens

Traver Hart, Amy H.Y. Tong, Katie Chan…·Jason Moffat

The paper evaluates CRISPR/Cas9 knockout screens in human cell lines and designs an optimized gRNA library to improve gene knockout efficiency and accuracy.

34 citations

humanCRISPR screen

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