Author

Andrea Habsid

University of Toronto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:CRISPR screen· 3 Approach:experimental assay· 3 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1

Frequent Co-Authors

Amy H.Y. TongiD· 4 shared Jason MoffatiD· 4 shared Kevin R. BrowniD· 4 shared Patricia Mero· 4 shared Brenda AndrewsiD· 3 shared Chad L. MyersiD· 3 shared Charles M. BooneiD· 3 shared Katherine ChaniD· 3 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersSystems Biology

Amy H.Y. TongORCID

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4 papers

Recent·Most cited

A global genetic interaction map of a human cell reveals conserved principles of genetic networks

Maximilian Billmann, Michael Costanzo, Xiang Zhang, Arshia Zernab Hassan, Mahfuzur Rahman, Kevin R. Brown, Katherine Chan, Amy H.Y. Tong, Carles Pons, Henry N. Ward, Catherine Ross, Jolanda S. van Leeuwen, Michael Aregger, Keith A. Lawson, Barbara Mair, , Charles M. Boone

The paper constructs a genome-scale genetic interaction network from 4 million double mutants in HAP1 cells, revealing conserved genetic network principles across species and uncovering novel gene functions and cancer dependencies.

bioRxiv · Jun 30, 2025 · PreprintSystems Biology

Systematic genome-scale identification of host factors for SARS-CoV-2 infection across models yields a core single gene dependency; ACE2

Katherine Chan, Adrian Granda Farias, Hunsang Lee, Furkan Guvenc, Patricia Mero, Kamaldeep Aulakh, Kevin R. Brown, Shahan Haider, Edyta Marcon, Ulrich Braunschweig, Amy H.Y. Tong, Shuye Pu, Andrea Habsid, Natasha Christie-Holmes, Patrick Budylowski, , Jason Moffat

The paper identifies ACE2 as the only common host dependency for SARS-CoV-2 across multiple cell lines, while other host factors are cell line specific.

bioRxiv · Jun 28, 2021 · PreprintSystems Biology

Systematic mapping of genetic interactions for de novo fatty acid synthesis

Michael Aregger, Keith A. Lawson, Maximilian Billmann, Michael Costanzo, Amy H.Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Ušaj, Lucy Nedyalkova, Olga S. Sizova, Andrea Habsid, Judy Pawling, Zhen‐Yuan Lin, , Jason Moffat

This study maps genetic interactions in FASN-deficient cells to identify genes involved in lipid uptake and metabolic adaptation.

Nature Metabolism · Jun 1, 2020Peer-reviewedSystems Biology

Evaluation and Design of Genome-wide CRISPR/Cas9 Knockout Screens

Traver Hart, Amy H.Y. Tong, Katie Chan, Jolanda S. van Leeuwen, Ashwin Seetharaman, Michael Aregger, Megha Chandrashekhar, Nicole Hustedt, Sahil Seth, Avery J. C. Noonan, Andrea Habsid, Olga S. Sizova, Lyudmila Nedyalkova, Ryan Climie, Keith A. Lawson, , Jason Moffat

The paper evaluates CRISPR/Cas9 knockout screens in human cell lines and designs an optimized gRNA library to improve gene knockout efficiency and accuracy.

bioRxiv · Mar 16, 2017 · PreprintSystems Biology