Author

Louis B. G. Cortes

Cornell UniversityORCID 0000-0003-3447-8769Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Organism:E. coli· 1

Frequent Co-Authors

Guillaume LambertiD· 2 shared David A. SpechtiD· 1 shared Miles V. RouchesiD· 1 shared Yasu XuiD· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

4 top collaborators · 4 mutual co-author links

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2 shared papersSynthetic Biology

Guillaume LambertORCID

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2 papers

Recent·Most cited

Synthetic BiologyACS Synthetic BiologyPeer-reviewedAug 26, 2022

Overcoming leak sensitivity in CRISPRi circuits using antisense RNA sequestration and regulatory feedback

David A. Specht, Louis B. G. Cortes, Guillaume Lambert

This paper improves CRISPRi circuits in E. coli by using antisense RNA sequestration and feedback to reduce leakiness and enhance logical function.

12 citations

E. coliCRISPR screen

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Synthetic BiologyNature CommunicationsPeer-reviewedJul 7, 2022

A Plasmid System with Tunable Copy Number

Miles V. Rouches, Yasu Xu, Louis B. G. Cortes, Guillaume Lambert

This paper introduces two plasmid systems for tunable copy number control and investigates their effects on bacterial growth, gene expression, and metabolic burden.

134 citationstop 1%

bacteria (other)experimental assay

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