Yijun Tian

The paper introduces nanoASM, a method for allele-specific methylation analysis using long-read sequencing, identifying functional noncoding variants in prostate cancer.

This paper uses nanopore long-read sequencing to characterize native CpG methylation and identify allele-specific methylation regions in the prostate genome.

This study uses multiome single-cell sequencing to identify regulatory eQTLs in prostate cancer risk loci, finding overlaps with bulk eQTLs and validating new regulatory SNPs.

This study identifies 5hmC-based gene set activity scores in cfDNA as biomarkers for early detection of ADT resistance in prostate cancer.

The paper identifies a regulatory SNP rs60464856 that increases RUVBL1 expression and contributes to prostate cancer progression through cohesin-CTCF binding and cell-cycle activation.