Developmental BiologybioRxivPreprint
Age-associated aberrations of cumulus-oocyte interaction and microfilamentous structure in the zona pellucida decline female fertility
Yu Ishikawa-Yamauchi, Chihiro Emori, Hideto Mori…·Masahito Ikawa
This study shows that age-related structural changes in the zona pellucida reduce fertilization rates in mice by impairing cumulus-oocyte interactions and sperm binding.
DOI 10.1101/2023.12.30.573680