BioinformaticsbioRxivPreprint
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STARsolo: accurate, fast and versatile mapping/quantification of single-cell and single-nucleus RNA-seq data
Benjamin Kaminow, Dinar Yunusov, Alexander Dobin
Genome-aligning STARsolo matches simulated truth (R≈0.99) and CellRanger's counts almost exactly, running up to 4.4 times faster than CellRanger; pseudoaligners call hundreds of false-positive genes per cell.