BiochemistryJournal of Chemical Information and ModelingPeer-reviewed
CACHE Challenge #1: targeting the WDR domain of LRRK2, a Parkinson's Disease associated protein.
Fengling Li, Suzanne Z. Ackloo, C. H. Arrowsmith…·Matthieu Schapira
The paper evaluates computational hit-finding methods for targeting the WDR domain of LRRK2, a Parkinson's disease protein, finding that diverse strategies yielded weakly potent compounds.
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