Author

Fengling Li

University of TorontoORCID 0000-0001-9530-2068Unclaimed ORCID profile · follow to get notified of new preprints

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Fengling Li1 paper

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:protein structure· 1

Frequent Co-Authors

A. M. EdwardsiD· 2 shared Aiping DongiD· 2 shared Albina Bolotokova· 2 shared C. H. ArrowsmithiD· 2 shared Elisa GibsoniD· 2 shared Hong ZengiD· 2 shared Irene ChauiD· 2 shared Levon HalabelianiD· 2 shared

Activity by Year

2024-2024 · peak 2/yr

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10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

A. M. EdwardsORCID

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2 papers

Recent·Most cited

BiochemistryJournal of Chemical Information and ModelingPeer-reviewedNov 5, 2024

CACHE Challenge #1: targeting the WDR domain of LRRK2, a Parkinson's Disease associated protein.

Fengling Li, Suzanne Z. Ackloo, C. H. Arrowsmith…·Matthieu Schapira

The paper evaluates computational hit-finding methods for targeting the WDR domain of LRRK2, a Parkinson's disease protein, finding that diverse strategies yielded weakly potent compounds.

34 citationstop 4%

deep learningdrug response / drug discovery

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BiochemistryJournal of Medicinal ChemistryPeer-reviewedNov 4, 2024

A resource to enable chemical biology and drug discovery of WDR Proteins

Suzanne Z. Ackloo, Fengling Li, Magda Szewczyk…·C. H. Arrowsmith

The paper develops a resource for discovering ligands for WDR proteins using experimental and computational methods, leading to the identification of drug-like ligands for 9 out of 20 targets.

28 citations

humanprotein structure

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