Aisha Haley Bianchi

The paper investigates eIF3 interactions with miRNAs during early T cell activation, finding that eIF3 binds miR-17~92 cluster miRNAs and that their disruption affects T cell activation markers.

The paper uses deep mutational scanning to analyze CYP2C19 variants, revealing a tradeoff between substrate specificity and protein abundance.

MaveDB v2 curates over three million variant effects from MAVE studies to facilitate analysis and dissemination of functional assay data.