Author

Timothy James McDonald

University of ExeterORCID 0000-0003-3559-6660Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 3 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:GWAS / association mapping· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Assay:metabolomics· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Adem Y. DawediD· 3 shared Andrea MariiD· 3 shared Andrew Tym HattersleyiD· 3 shared Angus G. JonesiD· 3 shared Anubha MahajaniD· 3 shared Giuseppe Nicola GiordanoiD· 3 shared Hartmut Ruetten· 3 shared Hugo FitipaldiiD· 3 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersGenetic & Genomic Medicine

Adem Y. DawedORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Genetic & Genomic MedicineNature CommunicationsPeer-reviewedAug 21, 2023

Genetic analysis of blood molecular phenotypes reveals regulatory networks affecting complex traits: a DIRECT study.

Andrew Anand Brown, Juan J. Fernandez-Tajes, Mun‐Gwan Hong…·Ulrik Plesner Jacobsen

The paper identifies shared genetic regulation across mRNA, proteins, and metabolites in blood, revealing networks and mediators of GWAS variants.

44 citationstop 2%

humanbulk RNA-seq

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Genetic & Genomic MedicineThe Lancet Diabetes & EndocrinologyPeer-reviewedDec 15, 2022

Pharmacogenomics of GLP-1 Receptor Agonists: A genome-wide analysis of observational data and large randomized controlled trials

Adem Y. Dawed, Andrea Mari, Andrew Anand Brown…·A. Jonsson

This study identifies genetic variants associated with glycaemic response to GLP-1 receptor agonists using observational and trial data, finding variants in GLP-1R and ARRB1 linked to HbA1c reduction.

137 citationstop 1%

humanGWAS summary statistics

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Genetic & Genomic MedicinePLoS MedicinePeer-reviewedJun 19, 2020

Predicting and elucidating the etiology of fatty liver disease using a machine learning-based approach: an IMI DIRECT study

Naeimeh Atabaki‐Pasdar, Mattias Ohlsson, Ana Viñuela…·Paul W. Franks

This study develops machine learning models to predict liver fat content using multi-omic and clinical data from NAFLD patients, achieving higher accuracy than existing tools.

97 citationstop 1%

humanmetabolomics

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GenomicsGastroenterologyPeer-reviewedOct 7, 2019

HLA-DQA1*05 is associated with the development of antibodies to anti-TNF therapy

Aleksejs Sazonovs, Nicholas Alexander Kennedy, Loukas Moutsianas…·Thankam Paul

This study identifies HLA-DQA1*05 as a genetic risk factor for anti-drug antibody development in Crohn's disease patients treated with anti-TNF therapies.

424 citationstop 1%

humanstatistical model

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