HLA-DQA1*05 is associated with the development of antibodies to anti-TNF therapy
Aleksejs Sazonovs, Nicholas Alexander Kennedy, Loukas Moutsianas, Graham Heap, Daniel L Rice, Mark Reppell, Claire Bewshea, Neil Chanchlani, G Walker, Mandy H. Perry, Timothy James McDonald, Charlie W. Lees, Fraser J.R. Cummings, Miles Parkes, John C. Mansfield, , Thankam Paul
This study identifies HLA-DQA1*05 as a genetic risk factor for anti-drug antibody development in Crohn's disease patients treated with anti-TNF therapies.
Gastroenterology · Oct 7, 2019Peer-reviewedGenomics