Author

Drew W. Pratt

National Institutes of HealthORCID 0000-0003-3583-8308Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Alejandro A. SchäfferiD· 1 shared Alnawaz Rehemtualla· 1 shared Andrew J. ScottiD· 1 shared Angela K. Walker· 1 shared Barbara Scott NelsoniD· 1 shared Christian K. WerneriD· 1 shared Christopher J. HalbrookiD· 1 shared Costas Andreas LyssiotisiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBioinformatics

Alejandro A. SchäfferORCID

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2 papers

Recent·Most cited

BioinformaticsGenome ResearchPeer-reviewedJun 14, 2023

Single-cell methylation sequencing data reveal succinct metastatic migration histories and tumor progression models

Yuelin Liu, Xuan Cindy Li, Farid Rashidi Mehrabadi…·S. Cenk Şahinalp

This paper introduces Sgootr, a method to infer tumor lineage trees from single-cell methylation data, revealing metastatic progression models and identifying lineage-informative CpG sites.

9 citations

humanDNA methylation

𝕏 PostBluesky

NeuroscienceNature CommunicationsPeer-reviewedJul 30, 2020

Purine metabolism regulates DNA repair and therapy resistance in glioblastoma

Weihua Zhou, Yangyang Yao, Andrew J. Scott…·Daniel Richard Wahl

This study shows that purine metabolism affects DNA repair and therapy resistance in glioblastoma, suggesting that targeting purine synthesis could improve treatment outcomes.

243 citationstop 1%

humanbulk RNA-seq

𝕏 PostBluesky