Author

Tina Begum

SIB Swiss Institute of BioinformaticsORCID 0000-0003-3618-473XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:multiple species· 1 Assay:whole-genome sequencing· 1 Organism:yeast· 1

Frequent Co-Authors

Christabel Floi BucaoiD· 1 shared Debarun AcharyaiD· 1 shared Manish Prakash VictoriD· 1 shared Marc Robinson‐RechaviiD· 1 shared Pablo DucheniD· 1 shared Tapash Chandra Ghosh· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 6 mutual co-author links

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1 shared paperEvolutionary Biology

Christabel Floi BucaoORCID

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2 papers

Recent·Most cited

Evolutionary BiologybioRxivPreprintDec 29, 2023

Sudden shifts in expression after small-scale duplication in vertebrates and strong support for the ortholog conjecture

Tina Begum, Pablo Duchen, Christabel Floi Bucao, Marc Robinson‐Rechavi

The paper tests the ortholog conjecture by analyzing gene expression shifts after duplication in vertebrates, finding strong support for the conjecture and showing trait jumps affect small-scale paralogs more than genome-wide duplicates.

DOI 10.1101/2023.12.29.571877

multiple speciesbulk RNA-seq

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BioinformaticsGenomicsPeer-reviewedSep 1, 2018

The optimization of mRNA expression level by its intrinsic properties -- insights from codon usage pattern and structural stability of mRNA

Manish Prakash Victor, Debarun Acharya, Tina Begum, Tapash Chandra Ghosh

The paper investigates how codon usage bias and mRNA structural stability influence gene expression in yeast, showing their combined role in optimizing expression levels.

27 citations

yeastDNA methylation

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