Author

Jacob Kochukaleekal John

Christian Medical College, VelloreORCID 0000-0003-3654-5099Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 3 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Organism:human· 3 Assay:whole-genome sequencing· 3 Research Focus:phylogenetics / evolution· 2 Organism:bacteria (other)· 1 Research Focus:genome assembly· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Balaji VeeraraghavaniD· 4 shared Jobin John JacobiD· 4 shared Ankur MutrejaiD· 3 shared Aravind Velmurugan· 3 shared Gagandeep KangiD· 3 shared Agila Kumari PragasamiD· 2 shared Karthick VasudevaniD· 2 shared Monisha Priya Teekaraman· 2 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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4 shared papersGenomics

Balaji VeeraraghavanORCID

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4 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJun 3, 2026

Development and validation of a genome-informed multiplex PCR for specific detection of typhoidal Salmonella serovars

Jobin John Jacob, T Praveen, Pavithra Sathya Narayanan…·Balaji Veeraraghavan

The paper develops and validates a genomics-informed multiplex PCR assay to specifically detect typhoidal Salmonella serovars, achieving high specificity and sensitivity.

DOI 10.64898/2026.06.01.729223

bacteria (other)statistical model

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GenomicsMicrobiology SpectrumPeer-reviewedApr 10, 2025

Recent emergence of cephalosporin resistant Salmonella Typhi in India due to the endemic clone acquiring IncFIB(K) plasmid encoding blaCTX-M-15 gene

Tharani Priya Thirumoorthy, Jobin John Jacob, Aravind Velmurugan…·Balaji Veeraraghavan

15 citationstop 3%

humanwhole-genome sequencing

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GenomicsPLoS PathogensPeer-reviewedApr 28, 2023

Genomic analysis unveils the role of genome degradation events and gene flux in the emergence and persistence of S. Paratyphi A lineages

Jobin John Jacob, Agila Kumari Pragasam, Karthick Vasudevan…·Ankur Mutreja

The paper analyzes S. Paratyphi A isolates to show genome degradation and gene flux drive lineage evolution, with implications for public health surveillance.

4 citations

humanwhole-genome sequencing

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GenomicsGenomicsPeer-reviewedMay 12, 2021

Salmonella Typhi acquires diverse plasmids from other Enterobacteriaceae to develop cephalosporin resistance

Jobin John Jacob, Agila Kumari Pragasam, Karthick Vasudevan…·Ankur Mutreja

This study analyzes ceftriaxone-resistant Salmonella Typhi isolates from India, finding that resistance arises from plasmid acquisition, with IncX3 and IncN plasmids contributing to sporadic resistance while IncY plasmids are associated with outbreaks in Pakistan.

38 citations

humanwhole-genome sequencing

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