Recent emergence of cephalosporin resistant Salmonella Typhi in India due to the endemic clone acquiring IncFIB(K) plasmid encoding blaCTX-M-15 gene
Tharani Priya Thirumoorthy, Jobin John Jacob, Aravind Velmurugan…·Balaji Veeraraghavan
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University of CambridgeORCID 0000-0002-1118-8075Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
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Tharani Priya Thirumoorthy, Jobin John Jacob, Aravind Velmurugan…·Balaji Veeraraghavan
Jobin John Jacob, Agila Kumari Pragasam, Karthick Vasudevan…·Ankur Mutreja
The paper analyzes S. Paratyphi A isolates to show genome degradation and gene flux drive lineage evolution, with implications for public health surveillance.
Jobin John Jacob, Karthick Vasudevan, Agila Kumari Pragasam…·Ankur Mutreja
The paper analyzes SARS-CoV-2 genetic variants to identify stabilizing and destabilizing mutations and their impact on viral protein structure and function.
Jobin John Jacob, Agila Kumari Pragasam, Karthick Vasudevan…·Ankur Mutreja
This study analyzes ceftriaxone-resistant Salmonella Typhi isolates from India, finding that resistance arises from plasmid acquisition, with IncX3 and IncN plasmids contributing to sporadic resistance while IncY plasmids are associated with outbreaks in Pakistan.
Dhiviya Prabaa Muthuirulandi Sethuvel, Ankur Mutreja, Agila Kumari Pragasam…·Balaji Veeraraghavan
The paper analyzes genomic data from Shigella species in India, showing long-term persistence of S. flexneri and recent dominance of ciprofloxacin-resistant S. sonnei clones.
Naveen Kumar Devanga Ragupathi, Balaji Veeraraghavan, Dhiviya Prabaa Muthuirulandi Sethuvel…·Ankur Mutreja
The paper reports the first whole-genome analysis of multidrug-resistant E. coli isolates from bloodstream infections in India, identifying key resistance and virulence gene profiles.