Martin Z. Medrano

The paper shows biological age and age acceleration in blood predict Alzheimer's disease plasma biomarker levels in a Hispanic cohort.

The paper examines rare missense and loss of function variants in GWAS loci for Alzheimer's disease across families, finding that many families lack identifiable variants beyond APOE-e4.

The paper identifies rare FN1 variants that protect APOEε4 carriers from Alzheimer's disease by modulating extracellular matrix deposition and gliosis.

This study compares imputation accuracy for rare and ultra-rare variants in an admixed Caribbean Hispanic population using different reference panels and tools, finding that larger reference panels improve imputation quality.