GenomicsExperimental Hematology and OncologyPeer-reviewed
Three-dimensional chromatin landscapes in MLLr AML
Pinpin Sui, Zhihong Wang, Peng Zhang, Feng Pan
This study investigates 3D chromatin structure changes in MLLr AML using gene-edited samples, revealing specific alterations in chromatin accessibility, compartments, TADs, and loops that impact gene expression and leukemia development.