Diana M. Mitchell

This study shows microglia support rod photoreceptor regeneration in larval zebrafish, but Nrf2-independent mechanisms handle redox functions during regeneration.

This paper introduces space-time light-sheet microscopy (ST-LSM), a single-objective technique that improves imaging volume and field of view while maintaining resolution.

This study examines the regenerative response in zebrafish retinas after cone photoreceptor ablation, comparing microglia-sufficient and -deficient conditions, and identifies compensatory immune cell responses.

This study shows that microglia in zebrafish retinas clear ROS from dying rod photoreceptors, preventing oxidative stress and off-target cell death.

The paper uses real-time imaging of zebrafish retinas to show intercellular exchanges between Müller glia and microglia during apoptotic cell clearance.

The paper investigates microglial phagocytosis of apoptotic cells in the developing zebrafish retina and shows that P2RY12 signaling is required for timely clearance.