Author

Gustavo Pierdominici‐Sottile

National University of QuilmesORCID 0000-0003-3792-4509Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:mechanistic / dynamical model· 2 Research Focus:protein folding & dynamics· 2 Approach:Bayesian inference· 1 Research Focus:cell signaling & trafficking· 1 Assay:electrophysiology· 1

Frequent Co-Authors

Agustín OrmazábaliD· 1 shared Juliana PalmaiD· 1 shared Luciano MoffattiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

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3 top collaborators · 1 mutual co-author link

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1 shared paperBiophysics

Agustín OrmazábalORCID

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2 papers

Recent·Most cited

BiophysicsPhysical Chemistry Chemical PhysicsPeer-reviewedJan 1, 2026

Towards the Rational Design of RsmE Small-RNA Binders: Insights from Molecular Dynamics Simulations

Agustín Ormazábal, Juliana Palma, Gustavo Pierdominici‐Sottile

The paper uses molecular dynamics simulations to study RsmZ-RsmE interactions, revealing how RNA structure and linker regions affect binding affinities and informing the design of synthetic sRNAs.

DOI 10.1039/d6cp01010e

mechanistic / dynamical modelprotein folding & dynamics

𝕏 PostBluesky

BiophysicsbioRxivPreprintJun 20, 2025

Bayesian inference of functional asymmetry in a ligand-gated ion channel

Luciano Moffatt, Gustavo Pierdominici‐Sottile

The paper uses Bayesian inference and molecular dynamics to show asymmetric coupling in P2X2 receptors, explaining negative cooperativity and the flip state.

DOI 10.1101/2025.06.20.660684

electrophysiologyBayesian inference

𝕏 PostBluesky