Author

Michal Polonsky

California Institute of TechnologyORCID 0000-0003-3871-460XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Jina YuniD· 2 shared Long CaiiD· 2 shared Matt W. ThomsoniD· 2 shared Aharon NachshoniD· 1 shared Andrew P. McMahoniD· 1 shared Barbara J. WoldiD· 1 shared Brian A. WilliamsiD· 1 shared Guo‐Cheng YuaniD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCancer Biology

Jina YunORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 19, 2026

Spatial second-order features predict glioma malignant transformation

Michal Polonsky, Jonathan J. Fox, Yunrui Lu…·Long Cai

This study identifies second-order spatial features, such as ligand-receptor interactions, as predictive of glioma malignant transformation using integrated spatial DNA and RNA profiling.

DOI 10.64898/2026.08.14.744974

humanspatial transcriptomics

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Molecular BiologybioRxivPreprintNov 22, 2023

Spatial transcriptomics defines injury-specific microenvironments in the adult mouse kidney and novel cellular interactions in regeneration and disease

Michal Polonsky, Louisa Maria Sophie Gerhardt, Jina Yun…·Andrew P. McMahon

The paper uses spatial transcriptomics to identify injury-specific microenvironments and molecular interactions in the mouse kidney during injury and regeneration.

7 citations

mousespatial transcriptomics

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GenomicsProceedings of the National Academy of SciencesPeer-reviewedOct 12, 2021

Dynamic changes in tRNA modifications and abundance during T-cell activation

Roni Rak, Michal Polonsky, Inbal Eizenberg-Magar…·Yitzhak Pilpel

The paper examines dynamic changes in tRNA modifications and abundance during T-cell activation, finding reduced wybutosine and ms2t6A modifications that may increase ribosomal frameshifting and facilitate HIV infection.

69 citations

humanbulk RNA-seq

𝕏 PostBluesky