Author

Chan-Wang J. Lio

The Ohio State UniversityORCID 0000-0003-3876-6741Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Abhijit ChakrabortyiD· 1 shared Anjana RaoiD· 1 shared Benjamin DelatteiD· 1 shared Daniela Samaniego-Castruita· 1 shared David G. Schatz· 1 shared Edahi González-Avalos· 1 shared Fang-Yun Lay· 1 shared Ferhat AyiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

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10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Abhijit ChakrabortyORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintAug 24, 2025

MNase stratification reveals heterogeneous 5hmC in naive B cells

Michael Hsu, Heng-Yi Chen, Fang-Yun Lay…·Chan‐Wang Jerry Lio

The paper uses MNase digestion to stratify 5hmC in naive B cells, revealing that most 5hmC is nucleosome-associated, with minor subsets showing distinct chromatin accessibility patterns.

DOI 10.1101/2025.08.24.672045

mouseDNA methylation

𝕏 PostBluesky

ImmunologybioRxivPreprintOct 8, 2018

TET enzymes augment AID expression via 5hmC modifications at the Aicda superenhancer

Chan-Wang J. Lio, Vipul Shukla, Daniela Samaniego-Castruita…·Anjana Rao

This study shows TET enzymes enhance Aicda expression by depositing 5hmC at its superenhancer, promoting chromatin accessibility and CSR in B cells.

DOI 10.1101/438531

mouseChIP-seq

𝕏 PostBluesky