Author

Miranda A. Pan

University of California, IrvineORCID 0000-0003-3914-2578Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Ali MortazaviiD· 1 shared Andrea J. TenneriD· 1 shared Ángela Gómez-ArboledasiD· 1 shared Gabriela Balderrama-GutierreziD· 1 shared Heidi Yahan LiangiD· 1 shared Klébea CarvalhoiD· 1 shared Nicole D. SchartziD· 1 shared Purnika SelvaniD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Ali MortazaviORCID

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1 paper

Recent·Most cited

NeuroscienceActa Neuropathologica CommunicationsPeer-reviewedAug 17, 2022

C5aR1 antagonism alters microglial polarization and mitigates disease progression in a mouse model of Alzheimers disease

Ángela Gómez-Arboledas, Klébea Carvalho, Gabriela Balderrama-Gutierrez…·Andrea J. Tenner

The paper shows that C5aR1 antagonism reduces amyloid load and dystrophic neurites in a mouse model of Alzheimer's disease, shifting microglial polarization toward a neuroprotective phenotype.

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mouseexperimental assay

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