NeuroscienceProceedings of the National Academy of SciencesPeer-reviewed
Loss of primary cilia and dopaminergic neuroprotection in pathogenic LRRK2-driven and idiopathic Parkinsons disease
Shahzad S. Khan, Ebsy Jaimon, Yu‐En Lin…·Suzanne R. Pfeffer
The paper shows that loss of primary cilia in specific striatal cell types reduces dopaminergic neuroprotection in Parkinson's disease, linked to impaired Hedgehog signaling.