Author

Grant A. Armstrong

Lehigh UniversityORCID 0000-0003-4016-6841Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:machine learning (classical)· 1 Assay:protein sequence· 1 Research Focus:variant effect prediction· 1

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Brian Yuan CheniD· 1 shared Justin Z. TamiD· 1 shared Yangying LiuiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperBioinformatics

Brian Yuan ChenORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintOct 26, 2023

MechPPI: Binding Mechanism-based Machine-Learning tool for Predicting Protein-Protein Binding Affinity Changes Upon Mutations

Yangying Liu, Grant A. Armstrong, Justin Z. Tam, Brian Yuan Chen

MechPPI predicts protein-protein binding affinity changes due to mutations by using mechanism-based features, showing accuracy in single mutation analysis.

2 citations

protein sequencemachine learning (classical)

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