Yidan Sun

The paper develops Nanopore-HiChIP to map enhancer hubs and shows they buffer allelic regulatory variation through kinetic compensation, preserving balanced transcriptional output.

SnakeHichipTF decodes TF logic in enhancer-promoter wiring in human brain regions, revealing distinct regulatory programs and evolutionary elements.

SnakeAltPromoter provides a reproducible framework for differential alternative promoter analysis using RNA-seq, benchmarked against CAGE data and scalable for large datasets.

PEhub identifies multi-way enhancer hubs in human brain regions using HiChIP data, revealing their hierarchical organization and association with transcriptional output and genetic risk.