Directed Evolution of a Genetically Encoded Indicator for Chloride
Weicheng Peng, Jasmine N. Tutol, Shelby M. Phelps, Hiu C. Kam, Jacob K. Lynd, Sheel C. Dodani
The paper uses directed evolution to create a chloride-sensitive fluorescent protein indicator called ChlorOFF by mutating OFPxm.
ACS Synthetic Biology · Mar 21, 2025Peer-reviewedBiochemistry