Sirio Bolaños‐Puchet

The paper creates a detailed computational model of rat somatosensory cortex anatomy, including 4.2 million neurons and 14.2 billion synapses, and identifies limitations in connectivity prediction from morphology.

The paper presents a large-scale biophysically detailed model of somatosensory cortex to simulate and validate cortical dynamics and experimental results.

The paper uses simulations to study how synaptic plasticity interacts with network structure and dendritic organization to shape cortical microcircuit function and learning.

The paper presents a biophysically-detailed computational model of two interconnected cortical areas to study inter-areal interactions in sensory processing and their impact on stimulus discrimination and signal integration.

The paper enhances brain atlases with laminar coordinate systems and flatmaps to better represent layered brain regions, enabling improved visualization and modeling of structures like the barrel cortex.

The paper uses a simulation-based approach to study how synaptic connectivity patterns shape functional cell assemblies in a cortical network model, showing that connectivity structure significantly influences assembly composition and activation.