NeurosciencebioRxivPreprint
Brief exposure of neuronal cells to levels of short chain fatty acids observed in human systemic circulation impair the cell lipid metabolism resulting in associated cell death by apoptosis
Tiffany A. Fillier, Shrushti Shah, Karen M. Doody…·Raymond Thomas
This study shows that short chain fatty acids at systemic circulation levels alter brain lipid metabolism and impair neuronal cell function through mitochondrial dysfunction and apoptosis.