Author

Jacqueline J. Blundell

Memorial University of Newfoundland

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 2

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

Craig Stephen MooreiD· 1 shared Firoozeh Nafar· 1 shared Isabelle AubryiD· 1 shared Jessica C. BarroniD· 1 shared Karen M. DoodyiD· 1 shared Katelyn C Ryan· 1 shared Kelsie A Senior· 1 shared Laura J. Dawson· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperNeuroscience

Craig Stephen MooreORCID

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2 papers

Recent·Most cited

Huntingtin is essential for synaptic plasticity in the adult hippocampus

Jessica C. Barron, Laura J. Dawson, Samantha J. Carew, Mackenzie C. Grace, Kelsie A Senior, Katelyn C Ryan, Firoozeh Nafar, Craig Stephen Moore, Jacqueline J. Blundell, Matthew P. Parsons

This study shows that wild-type huntingtin (wtHTT) is essential for synaptic plasticity in the adult hippocampus, as its loss impairs long-term potentiation and post-tetanic potentiation.

Neurobiology of Disease · Jan 22, 2025Peer-reviewedNeuroscience

Brief exposure of neuronal cells to levels of short chain fatty acids observed in human systemic circulation impair the cell lipid metabolism resulting in associated cell death by apoptosis

Tiffany A. Fillier, Shrushti Shah, Karen M. Doody, Thu Huong Pham, Isabelle Aubry, Michel L. Tremblay, Sukhinder Kaur Cheema, Jacqueline J. Blundell, Raymond Thomas

This study shows that short chain fatty acids at systemic circulation levels alter brain lipid metabolism and impair neuronal cell function through mitochondrial dysfunction and apoptosis.

bioRxiv · Jun 1, 2021 · PreprintNeuroscience