Zian Wang

Hi-Cformer models multi-scale chromatin contact maps from single-cell Hi-C data, improving cell type separation and imputation of 3D genome features.

HitAnno annotates cell types in atlas-level scATAC-seq data using a hierarchical language model, accurately handling major and rare cell types across multiple settings.

The paper introduces Human-scATAC-Corpus, a database of human scATAC-seq data, and presents a foundation model for epigenomic analysis.

EpiAgent is a foundation model for single-cell epigenomic data that excels in feature extraction, cell annotation, and data imputation.