Author

Michal Cohen

Rambam Health Care CampusORCID 0000-0003-4209-7624Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:protein structure· 1 Approach:statistical model· 1

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Anna Fassler BakhmaniD· 1 shared Mickey KosloffiD· 1 shared Rachel KolodnyiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperBioinformatics

Anna Fassler BakhmanORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintDec 26, 2024

Structure-based mechanistic principles underlying the paradoxical effects of pathological RET mutations

Anna Fassler Bakhman, Michal Cohen, Rachel Kolodny, Mickey Kosloff

This study identifies structural mechanisms explaining how certain RET mutations cause both Hirschsprungs disease and MEN2A by disrupting protein structure and promoting dimerization.

DOI 10.1101/2024.12.26.630356

humanprotein structure

𝕏 PostBluesky