Anna Fassler Bakhman

The paper compares structural conservation and divergence across 245 RTK extracellular domains from 54 RTKs, revealing inter-family similarities and unexpected structural differences.

This study identifies residue-level differences in G13 interactions with p115RhoGEF and PDZRhoGEF, revealing molecular determinants of their differential recruitment and providing insights for targeted therapeutic strategies.

This study identifies structural mechanisms explaining how certain RET mutations cause both Hirschsprungs disease and MEN2A by disrupting protein structure and promoting dimerization.

This study identifies GABAB receptor homologs in Nematostella vectensis and shows that activating GABABR signaling inhibits neurogenesis and disrupts nervous system development.