Valeriia Timonina

The paper quantifies how mutational biases shape protein evolution in RNA viruses by analyzing SARS-CoV-2 and 34 other species, showing that mutational spectra predict amino acid composition changes and deviations indicate selection pressures.

The paper identifies genetic pathways and variants associated with sepsis susceptibility in children through genomic analysis of a paediatric cohort.

MosCoverY estimates mosaic loss of the Y chromosome from NGS sequencing data, showing comparable performance to existing methods and replicating known associations.

The paper investigates the role of mitochondrial DNA repeats in aging and healthspan, finding that disrupting the common repeat reduces somatic deletions and improves healthspan.